FLOW-MEDIATED VASODILATION CAN PREDICT SILENT ISCHEMIA: TWINS STUDY
نویسندگان
چکیده
منابع مشابه
Flow - Mediated Vasodilation *
Brachial arterial flow-mediated dilation (FMD), assessed by high-resolution ultrasonography, reflects endothelium-dependent vasodilator function. FMD is diminished in patients with atherosclerosis and with coronary risk factors, and improves with risk-reduction therapy. Therefore, the measurement of FMD can be a good prognostic instrument in preventive cardiology, is useful to predict short-ter...
متن کاملHaemoglobin and flow-mediated vasodilation.
A low [Hb] (Hb concentration) is out-balanced by peripheral vasodilation via mechanisms that are incompletely understood. Peripheral vasodilation is influenced by NO (nitric oxide) released from vascular endothelium in response to increased vessel wall shear stress, and absorption by Hb is the main mechanism by which the bioactivity of NO is disarmed. Thus we propose that graded NO absorption i...
متن کاملPrognostic significance of brachial flow-mediated vasodilation.
There is currently much research devoted to the study of vascular biology in intact humans. These efforts aim to translate findings from the basic science arena to a better understanding of the pathophysiology of atherosclerosis and its complications. Markers of vascular risk have been used as surrogate end points in treatment studies. More recently, long-term studies have emerged that speak to...
متن کاملFlow-mediated vasodilation partially reflects nitric oxide-mediated endothelial function.
To the Editor: In this Point:Counterpoint series, Green and Tschakovsky and Pyke address the issue of whether flowmediated dilation (FMD) reflects nitric oxide (NO)-mediated endothelial function (1). However, this question is difficult to answer. It has been conclusively shown that FMD of the brachial artery after 5 min of wrist cuff occlusion can be entirely abolished by the NO synthase (NOS) ...
متن کاملSilent Ischemia
Myocardial ischemia can occur without overt symptoms. In fact, asymptomatic (or silent) ST-segment depression during ambulatory electrocardiogram monitoring occurs more often than symptomatic ST-segment depression in patients with coronary artery disease. Initial studies documented that silent ischemia provided independent prediction of adverse outcomes in patients with known and unknown corona...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2010
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(10)60621-3